Antiplatelet Drugs and Endothelial Function
نویسندگان
چکیده
منابع مشابه
Antiplatelet Drugs and Endothelial Function
Antiplatelets drugs, particularly cilostazol, an inhibitor of phosphodiesterase (PDE), are widely used for the treatment of ischemic stroke, transient ischemic attack, and peripheral arterial disease (PAD). The use of cilostazol reduces cardiovascular morbidity and mortality in patients with PAD as well as in patients with coronary artery disease (CAD) 1). Although the mechanisms underlying the...
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Antiplatelet drugs protect against myocardial infarction, stroke, cardiovascular death and other serious vascular events in patients with a history of previous vascular events or known risk factors for cardiovascular disease. Aspirin reduces the risk of serious vascular events in patients at high risk of such an event by about a quarter and is recommended as the first-line antiplatelet drug. Cl...
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10.2217/14750708.2.3.465 © 2 part of latelets play an important, life-saving role in hemostasis and blood clotting at sites of ascular injury. However, unwanted platelet activation and arterial thrombus formation are mplicated in the onset of myocardial infarction, stroke and other cardiovascular diseases. ifferent mechanisms, such as vascular damage, the development of mural platelet thrombi s...
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Little intravascular coagulation of blood occurs in normal physiological conditions. Hemostasis involves the interplay of three procoagulant phases (vascular, platelet, and coagulation) that promote blood clotting to prevent blood loss (Fig. 22.1). The fibrinolytic system prevents propagation of clotting beyond the site of vascular injury and is involved in clot dissolution, or lysis (Fig. 22.2...
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INTRODUCTION Platelets are vital components of normal hemostasis and key participants in pathologic thrombosis by virtue of their ability to adhere to injured vessels and to accumulate at sites of injury. Platelets have long been recognized as primary participants in arterial thromboembolism (TE). More recently, their role in venous thrombosis has been elucidated. Antiplatelet drugs interfere w...
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ژورنال
عنوان ژورنال: Journal of Atherosclerosis and Thrombosis
سال: 2016
ISSN: 1340-3478,1880-3873
DOI: 10.5551/jat.ed054